Webinar of the Month | Dec 2017


Webinar on Unique Molecular Identifier-powered Ultra-sensitive Variant Calling using Strand NGS - Case Study


Abstract:

Unique Molecular Identifiers (UMIs) are short random nucleotide sequences that are increasingly being used in high-throughput sequencing experiments. In this webinar, we will highlight the UMI-friendly features of Strand NGS v3.1 including support for handling well known and customised UMI libraries, QC metrics, consensus alignment, UMI-based family size filters for read list, genome browser enabled with UMI-specific features and filters, UMI-aware variant calling parameters, and exporting UMI-tagged aligned samples. These all features together empower users to harness the potential of UMI-tagged NGS data for deeper insights. A case study demonstrating application of these UMI-based features in Strand NGS for low frequency variant calling in cfDNA sample will be presented.

UMI-tagged NGS libraries allow, ultra-sensitive detection of low frequency variants from liquid biopsy samples using DNA-Seq and accurate quantification of transcript-level expression using RNA-Seq. The recent release of Strand NGS v3.1, is equipped with the necessary features to efficiently analyse UMI-tagged NGS data helping researchers and labs involved in rare variant calling like in cfDNA based cancer diagnostics, and accurate transcript quantification with RNA-Seq.

Speaker:

Dr. Pandurang Kolekar, Bioinformatics Engineer, Strand Life Sciences

Webinar details

Sessions San Francisco Time
(PST)
Tokyo Time
(GMT+09:00)
Berlin Time
(GMT+01:00)
Mumbai Time
(GMT+05:30)
Session 1
SAPK/APFO
13 Dec
01:00 AM
13 Dec
06:00 PM
13 Dec
10:00 AM
13 Dec
02:30 PM
Session 2
AFO/ EMEA
13 Dec
08:00 AM
14 Dec
01:00 AM
13 Dec
05:00 PM
13 Dec
09:30 PM

Registrations open for this webinar

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